MicroRNA-203 contributes to skin re-epithelialization
نویسندگان
چکیده
منابع مشابه
Kindlin-1 contributes to EGF-induced re-epithelialization in skin wound healing
The commercial use of epidermal growth factor (EGF) is extensive and has been shown to be effective for skin wound healing in clinical practice. There is evidence to indicate that the topical administration of EGF significantly accelerates re-epithelialization by promoting keratinocyte mitogenesis and migration following acute injury; however, the mechanisms involved remain to be elucidated. Th...
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BACKGROUND Human lactoferrin (hLF), a member of the transferrin family, is known for its antimicrobial and anti-inflammatory effects. Recent studies on various nonskin cell lines indicate that hLF may have a stimulatory effect on cell proliferation. OBJECTIVES To study the potential role of hLF in wound re-epithelialization. MATERIALS AND METHODS The effects of hLF on cell growth, migration...
متن کاملCorneal re-epithelialization in galactosemic rats.
Abnormalities in corneal epithelial healing in diabetic patients have been described recently. Defects in corneal re-epithelialization in diabetic rats have been reported, and it was found that treatment with aldose reductase (AR) inhibitors effectively prevented these defects. Experiments using galactosemic rats to study further the role of AR in these defects, since AR is known to be the comm...
متن کاملLeptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair.
Wound-healing disorders are a therapeutic problem of extensive clinical importance. Leptin-deficient ob/ob mice are characterized by a severely delayed wound healing that has been explained by the mild diabetic phenotype of these animals. Here we demonstrate that systemically and topically supplemented leptin improved re-epithelialization of wounds in ob/ob mice. Leptin completely reversed the ...
متن کاملInducing re-epithelialization in skin wound through cultured oral mucosal keratinocytes
OBJECTIVES The purpose of this study was to investigate the wound healing effect of primary cultured oral mucosal keratinocytes (OMKs) and to assess their roles in skin wounds. MATERIALS AND METHODS OMK labeled with BromodeoxyUridine were scattered onto 1.5×1.5 cm skin defects of adult female nude mice (OMK group, n=15). For the control, culture media were placed on the wound (control group, ...
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ژورنال
عنوان ژورنال: Cell Death & Disease
سال: 2012
ISSN: 2041-4889
DOI: 10.1038/cddis.2012.174